Campus Company LoQus23 Therapeutics Hoping to Slow the Progression of Huntington's Disease
14/10/2024
LoQus23 Therapeutics Ltd (“LoQus23”), a private biotechnology company investigating small molecule drugs that could stop DNA instability and slow neurodegeneration in Huntington’s Disease, myotonic dystrophy type 1 and similar triplet repeat expansion diseases, today announces the successful close of its £35 million (c.$43 million) Series A financing.
Huntington’s disease is an autosomal dominant neurodegenerative disorder for which there is currently no disease modifying treatment available and which has 30,000 patients in the US alone. By targeting somatic expansion, LoQus23 is hoping to slow or even halt the onset and progression of Huntington’s disease, a concept supported by genetic studies and recently strengthened by pre-clinical models.
The proceeds of the Series A financing will be primarily used to support the pre-clinical development and initial clinical studies of LoQus23’s lead programme, an allosteric small molecule MutSβ inhibitor. The Company is preparing its lead programme to enter the clinic in 2026.
Congratulations to LoQus23 on their successful funding! If you would like to read more please click the link below.