Closing Date: 24/03/2023

About RxCelerate

The RxCelerate group is an out-sourced drug discovery and development platform specialising in the design and delivery of drug discovery and development programs for our clients spanning from an idea up to and including Phase II clinical studies.

We are currently looking to recruit a Senior Scientific Officer within our Preclinical division. Within this division, our in vivo scientists specialise in working with clients to develop bespoke preclinical animal models of disease, as well as investigating the tolerability and pharmacokinetics of potential therapeutics, as well as investigating the tolerability and pharmacokinetics of potential therapeutics.

The Role

Your primary responsibility will be to lead on the design, management and analysis of a broad range of in vivo studies. You are expected to have extensive experience in the design and conduct of animal studies and the role will provide a great variety in the projects undertaken. You should be self-motivated and able to organise, research and perform experiments effectively, accurately and to a high standard. You will work in multi-disciplinary collaborations with external scientists as well as other divisions within RxCelerate, involving a high level of teamwork.

Main Responsibilities

• Contribute expertise to the design and scientific research of in vivo projects.

• Coordinate and conduct in vivo studies.

• Analyse efficacy, tolerability and PK/PD data and produce reports to tight deadlines.

• Present data to key stakeholders.

• Assist in the supervision and training of staff.

• Work closely with other RxCelerate divisions to ensure the successful delivery and analysis of in vivo projects.

Skills/Requirements

Essential

• PhD (or equivalent) with experience of post-PhD research in industry or academia.

• Proven track record of independently planning and running in vivo studies with practical competencies in regulated procedures such as dosing (such as i.p., i.v., p.o., s.c.) and blood/tissue sampling.

• Experience of managing the operational and logistical aspects of in vivo studies.

• Significant experience of analysing and interpreting a broad range of datasets.

• Currently hold or have recently held a PIL.

• Excellent understanding of the regulatory and compliance aspects of in vivo work.

• High ethical standards with experience of applying the 3R’s.

• Excellent scientific communication skills, including the ability to write study proposals and reports as well as the ability to present data to a diverse audience.

• Flexible: ability to react to changing priorities and to work flexibly (out of hours working, including weekends, evenings and public holidays, is required for this post as necessary).

• Highly organised and self-motivated.

• Ability to multitask and work across multiple projects simultaneously.

• Excellent level of computer literacy.

Desirable

• Experience of setting up a new rodent model of disease.

• Experience of measuring pressure volume (PV) loops in rodents to assess cardiac function.

• Rodent surgical experience.

This is a full-time role, which includes weekend working when required by ongoing studies. RxCelerate offers a competitive salary with an annual bonus scheme, company pension and company benefit package.

You will be required to travel between sites with equipment within the Cambridge area; therefore, a driving licence and access to a car is essential.

Please send a cover letter, outlining how you meet the requirements above, and curriculum vitae in PDF format to careers@rxcelerate.com. Informal enquiries can also be directed to this email address.

RxCelerate values and actively supports equality, diversity and inclusion and encourages applications from all sections of society.