Immunology Scientist, Drug Discovery

F-star

Closing Date: 05/01/2022

A BIT ABOUT US… 
At F-star, we are dedicated to developing next generation immunotherapies to transform the lives of patients with cancer. We develop mAb², a novel class of disruptive bispecific antibody-based therapies that have the potential to overcome tumor resistance and restore anti-cancer immunity and responsiveness. 

We are committed to delivering life-changing treatments for the estimated 80% of patients with cancer who currently fail to have a durable response to immunotherapies. 

Our wholly owned pipeline shows focused and potent immune activation, with a promising safety profile to date. 

We’re an agile, international team with dual headquarters in Cambridge, UK and Cambridge, Massachusetts. We empower our teams to decide where and when they work to deliver our goals. 

 

YOUR ROLE IN OUR TEAM: 
Working within the Drug Discovery department, you will be accountable for designing, executing, and analysing in vitro assays to aid in drug discovery. You will also contribute to the identification of new targets for bispecific antibodies in immuno-oncology. As a Scientist you will use your knowledge and experience of immunology to contribute biology expertise to multi-functional immuno-oncology project teams. You will need to demonstrate good judgement and effective decision making in applying your expertise in understanding the underlying immunological response(s) to bispecific antibody intervention. 

 

YOUR KEY RESPONSIBILITIES WILL INCLUDE: 

  • Independently design, plan and execute experiments in this lab-based role, in line with project goals to support drug discovery 
  • Analyse and present data effectively to line managers, peers, and project teams 
  • Use expertise to optimise existing in vitro human primary PBMC assays, develop novel assays to characterise bispecific molecules, and train and mentor junior staff 
  • Influence project direction by providing immunological expertise to the Drug Discovery team 
  • Contribute to solving experimental challenges or technical difficulties within the department 
  • Maintain an up-to-date awareness of scientific literature and F-star relevant competitive intelligence 
  • Maintain up-to-date and accurate records of experiments and data 

 

A BIT ABOUT YOU: 
We’re looking for someone who is adaptable, keen to learn, and enthusiastic about optimising new methods. You’ll be organised with strong attention to detail and confident in delivering work with limited supervision. Communication skills are important along with the ability to

work well within teams. This is a busy role with deadlines to meet and so you’ll be able to prioritise your workload and adapt quickly to change when needed. 

 

YOUR SKILLS, KNOWLEDGE AND EXPERIENCE: 

Essential: 

  • PhD, or significant experience, in a biological subject with a focus on immunology, oncology and/or pharmacology 
  • Practical experience in the development and characterisation of primary human in vitro immunological assays, in particular T and/or NK cell biology 
  • Technically competent in multi-colour flow cytometry 
  • Experience in running immunoassays e.g. ELISAs, MSD, Gyrolab 

Desirable: 

  • Experience in antibody characterisation 

 

WHAT WE CAN OFFER TO YOU: 
We get things done, we keep things simple and we’re driven by the science. We’re ambitious so we work hard to create an environment where we can take smart risks. We want to be innovative so encourage debate and collaboration to challenge the usual way of doing things. We love our celebrations, socialising and perks, which make F-star a fun and diverse place to work. And most of all, everyone has the opportunity to make a difference. 

Benefits: 

  • Pension (8% Employer contribution) 
  • Equity Incentives 
  • Private Medical Insurance and Health Cash Plan 
  • Life assurance 
  • 25 days paid holiday, plus the option to buy 5 days 
  • Travel insurance 
  • Enhanced Maternity, Paternity, Adoption pay 
  • Agile working opportunities 

 

OTHER DETAILS: 

This role is to be based in Cambridge, UK. Our laboratories and office space are based on the Babraham Research Campus, South Cambridgeshire. 

This is a full-time position working 37.5 hours per week. F-star is proud to fully embrace agile working which gives you options in how, where and when you get your work done, including flexible working hours and home working. 

 

NEXT STEPS… 
If you feel this role is right for you, we’d love to hear from you. 

To apply, please visit our website: https://www.f-star.com/about/careers/ and upload your CV for us to view. Those that shine brightest will be contacted to discuss the role further, however, we aim to get back to everyone with a response either way. 

We may choose to close the role sooner than the application closing date depending on volume of candidates and so we encourage early applications. 

If, along the way, you experience any difficulties with applying via our website, please email HR@f-star.com

We aspire to be a diverse and inclusive workplace and strongly encourage suitably qualified applicants from a wide range of backgrounds to apply. 

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