Target Validation Scientist (4264)

Artios Pharma Limited

Closing Date: 31/03/2023

Outline of the role:

You will join a growing research team within this innovative and expanding company. Your primary responsibilities will be to support the DDR Biology team in contributing biological data to Artios’ early-stage drug discovery projects. You will use genetic, cell biological and pharmacological strategies to identify and validate therapeutic targets using cell-based systems and deliver high quality cell biological and mode of action data packages to understand target biology. You will also work in multi-disciplinary collaborations involving a high level of teamwork.

Responsibilities and Duties:

Apply expertise in cell and molecular biology to run mechanistic cell biological studies to validate Artios’ novel targets

Contribute biological data to Artios’ ongoing drug discovery projects

Qualifications and Experience:


PhD or equivalent in a life science subject

Proven experience working in a research environment


Experience of in vitro pharmacology or drug discovery

Experience working in an industrial setting will be a distinct advantage

Key Skills and Abilities:


Excellent skills in a broad range of cell and molecular biology techniques, including mammalian cell culture, viability assays, Western blotting and RNA interference

Understanding of DNA damage response biology, DNA repair pathways and/or cancer biology

High level of team working skills required

Ability to work independently as well as part of a team in an organised and methodical fashion

Ability to troubleshoot experiments independently

Excellent communication and presentation skills

Excellent attention to detail

Keeping accurate laboratory records

High level of IT literacy

Flexible approach to change


Expertise in fluorescence microscopy-based methods such as immunofluorescence

Expertise in flow cytometry

Experience of small molecule drug discovery

Experience with stable cell line generation

This is a permanent position, offering an attractive salary & benefits package. Appointment will be lab based at Scientist level. If you have the right background, then please apply on our website by sending your CV with a covering letter quoting Ref 4264.

In order to comply with UK Employment Law, all applicants must have the Right to Work in the UK or if from the EU, subject to receiving a relevant Skilled Worker Visa to work in the UK.

Due to the high volume of applications we receive, if you do not hear from us we will not be inviting you to interview on this occasion.